Fenyong Liu Selected Research

Catalytic RNA (Ribozymes)

1/2018	Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals.
1/2017	Inhibition of human cytomegalovirus immediate early gene expression and growth by a novel RNase P ribozyme variant.
1/2012	Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.
2/2011	Oral delivery of RNase P ribozymes by Salmonella inhibits viral infection in mice.
4/2010	Salmonella-mediated delivery of RNase P-based ribozymes for inhibition of viral gene expression and replication in human cells.
1/2010	Catalytic M1GS RNA as an antiviral agent in animals.
8/2008	Effective inhibition in animals of viral pathogenesis by a ribozyme derived from RNase P catalytic RNA.
5/2005	Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopy.
8/2003	Engineering of RNase P ribozyme for gene-targeting applications.
5/2003	Expression of an RNase P ribozyme against the mRNA encoding human cytomegalovirus protease inhibits viral capsid protein processing and growth.

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Fenyong Liu Research Topics

Disease

35	Infections 01/2021 - 08/2002
8	Virus Diseases (Viral Diseases) 01/2019 - 11/2005
4	Salmonella Infections (Salmonellosis) 06/2014 - 04/2009
3	Neoplasms (Cancer) 01/2017 - 08/2003
3	Bacterial Infections (Bacterial Infection) 09/2011 - 04/2009
2	Enterocolitis 01/2010 - 04/2009
1	Carcinogenesis 01/2019
1	Cytokine Release Syndrome 02/2018
1	Ankylosing Spondylitis 01/2018
1	Autoimmune Diseases (Autoimmune Disease) 01/2018
1	Latent Infection 01/2018
1	Alzheimer Disease (Alzheimer's Disease) 09/2016
1	Parkinson Disease (Parkinson's Disease) 09/2016
1	Spinal Cord Injuries (Spinal Cord Injury) 09/2016
1	Stroke (Strokes) 09/2016
1	Chronic Hepatitis B 03/2016
1	Atherosclerosis 11/2014
1	Starvation 11/2014
1	Persistent Infection 10/2013
1	HIV Infections (HIV Infection) 01/2012
1	Kaposi Sarcoma (Kaposi's Sarcoma) 06/2004
1	Primary Effusion Lymphoma 06/2004
1	Acquired Immunodeficiency Syndrome (AIDS) 06/2004
1	Cytomegalovirus Infections (Inclusion Disease) 08/2002

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2003
11	Catalytic RNA (Ribozymes)IBA 01/2018 - 08/2002
10	Ribonuclease P (RNase P)IBA 01/2018 - 08/2002
4	Antiviral Agents (Antivirals)IBA 01/2019 - 10/2006
4	MicroRNAs (MicroRNA)IBA 02/2018 - 11/2005
4	RNA (Ribonucleic Acid)IBA 02/2018 - 01/2010
4	Messenger RNA (mRNA)IBA 12/2017 - 05/2003
3	InterferonsIBA 01/2018 - 04/2005
3	DNA (Deoxyribonucleic Acid)IBA 10/2013 - 02/2006
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 03/2016
2	CytokinesIBA 02/2018 - 07/2003
2	Virulence Factors (Pathogenicity Factors)IBA 02/2018 - 09/2011
2	Caspase 3 (Caspase-3)IBA 01/2017 - 11/2014
2	Capsid Proteins (Capsid Protein)IBA 08/2013 - 01/2005
2	N- succinimidyl- 5- iodo- 3- pyridinecarboxylic acidIBA 06/2010 - 01/2010
2	Type III Secretion SystemsIBA 01/2010 - 04/2009
2	lambda Spi-1IBA 01/2010 - 04/2009
2	EpitopesIBA 01/2010 - 04/2009
1	Pharmaceutical PreparationsIBA 01/2021
1	Viral RNAIBA 02/2018
1	InflammasomesIBA 01/2018
1	UbiquitinIBA 01/2018
1	Untranslated Regions (Untranslated Region)IBA 12/2017
1	3' Untranslated Regions (3' UTR)IBA 12/2017
1	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 12/2017
1	Metalloproteases (Metalloproteinases)IBA 12/2017
1	Glycoproteins (Glycoprotein)IBA 12/2017
1	Chimeric Antigen ReceptorsIBA 01/2017
1	Retinaldehyde (Retinal)IBA 09/2016
1	Indicators and Reagents (Reagents)IBA 03/2016
1	Salmonella VaccinesIBA 01/2015
1	WortmanninIBA 11/2014
1	myocardinIBA 11/2014
1	AntagomirsIBA 06/2014
1	Macrophage Colony-Stimulating FactorIBA 06/2014
1	ElementsIBA 03/2014
1	CCR5 Receptors (CCR5 Receptor)IBA 01/2013
1	pgRNAIBA 01/2013
1	Protein Isoforms (Isoforms)IBA 01/2012
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 06/2010
1	LigandsIBA 10/2004
1	Interleukin-4 (Interleukin 4)IBA 07/2003
1	Interleukin-10 (Interleukin 10)IBA 07/2003

Therapy/Procedure

5	Therapeutics 01/2021 - 03/2016